Longevity genes

Men carrying two copies of an IDE(Insulin-degrading enzyme) gene variant tend to live longer than those with only one copy.

A daf2 gene mutation in nematode worms living on agar in laboratories gives the nematode worms a longer lifespan.

Those who have a`C' version of the gene/enzyme succinic semialdehyde dehydrogenase(SSADH) were more likely to reach 100 years old, this version of the gene is more efficient at riding the brain of excess acid.

Those with the 2`T' version of SSADH are unlikely to live past 85.

Variations within a gene called FOXO3A(associated with insulin signalling) are associated with longevity.

One variation with two copies of one version of the gene were less likely to report health problems and more likely to live to 98.

SIRT1 overexpression may affect the ageing process.

The E3 ubiquitin ligase wwp-1 with the transcription factor pha-4,but not the transctiption factor daf-16,together with calorie restriction can increase lifespan.

mutations in a gene called TOR can affect ageing

Alcohol related genes

ADH1B(alcohol dehyrogenase enzymes), a variant of this gene can metabolize alcohol 100 times faster than non-carriers of this gene variant.

A variant  of adh1b*3 found in African americans appears to be more likely to cause sleepiness when they drank alcohol.

Genes linked to hair colour

EDAR gene variants in asians cause thicker hair.
Search Amazon.com for asian genetics
Mutations in genes called MC1R and ASIP causes red hair and freckles, as well as increasing your chances of melanomas/skin cancer.

MC1R is more likely to give you skin cancer depending on exposure to sunlight ,whereas ASIP is less so.

SLC24A5

Tasmanian Tiger Genes

Scientists have extracted DNA from 4 Tasmanian Tiger, 3 of which are preserved in alcohol, isolating genes, then injecting them into mouse embryos.

Tests show a gene called Cola1 was switched on, causing bone and cartilage to grow in the young mice.

The last Tasmanian Tiger died in 1936.

Genes linked to pre-eclampsia

Some cases of pre-eclampsia could be caused by mutations in a gene that makes
2-methoxyoestradion, aka 2-ME, according to studies on mice.

Genes , IVF and embryo viability

Researchers have identified 7317 genetic instruction sets expressed by viable embryos but not by unviable embryos.

Researchers hope to find 10 top genes which predict which embryos become viable.

Genetic abbreviations

aaat
aak
aat;alpha-1 anti-trypsin
aba;abscisic acid
abca
abi
abl
ablim
acadl
acadm
acavl
accn
acH
achr;acetylcholine receptor
acj
acl;atp-citrate lycase
ACOT;acyl-coa thioesterase
acs2p
acsl
act;actin
acta2;a2-actin
actn;actinin
adamts
adfp;adipocyte differentation-related protein
ADH;alcohol dehyrogenase enzymes
adrp;adipocyte differentation-related protein
aep
ago;argonaute
ahr;aryl hydrocarbon receptor
aicd;app intracellular domain
aid;acivation-induced deaminase
aim
aipm;azaindolyl-pyrazinyl-maleimide
akt
ala
alas;aminolevulinic acid synthase
alb
alda-1
alai
aldh2;aldehyde dehydrogenase 2
alg
alk;anaplastic lymphoma kinase
alt;alanine aminotransferase
alu
ampa
ampk
amt
amy;amylase
anb
angpt;angiopoietin
anxa
ap;adaptor protein
apba;amyloid B A4 precursor protein-binding,family a
apc ;anaphase-promoting complex?/aenomarous plyposis coli/apythical protein kinase
apc/c;anaphase-promoting complex/cyclosome
aph
aplb
apoa
apobec;apolipoprotein B eiing complex proein
APOE
app;amyloid precursor protein
ap*s
aqp
ar;androgen receptor
araC
arc
ARF;adenosine diphosphate ribosylation factor
arg;arginine
arhgef7
asc
asf;ant-silencing unction
ash
asic
ASIP;agouti signaling protein
asn
asp
aspm
ast
ASXL
atf;activating transcription factor
atl;alkyltranserase-like protein
atm
atoh
atp;adenosine triphosphate
atr6v
avpr;arginine vasopressin
BAC;bacterial artificial chromosome
bach
bak
batp
bax
bbc
bcan
bcap;b cell adaptor protein
bcar
bcl
bcr;b cell receptors
bcr-abl1;B-cell recepor?
bdf
Bdnf;brain-derived neuorotrophic factor
becn;beclin
betp
bh
bhlh;;basic-helix-loop-helix
bid
bim
blimp
BMP;bone morphogenetic proteins
bmpr;ditto + recepttor
bolle
boule
bpi
braf
brap
BRCA
brct
brdU;bromodeoxyuridine
brn3
bs;blistered
btd; b tail domain
bubr;budding uninhibited by benzimidazoles-related
by
bzip;basic-region leucine zipper
b2m;b*-microgloin
b3gbt1
ca;chromatin assembly factor/cis-aconitate
caaatt
cacnp
caga
calcr;calcitonin receptor
caloco
camk;calcium/calmodulin-dependent kinase
camta;calmodulin-binding transcription activator
caps;capricious
card;caspase recruitment domain-containing protein
carm;coativator-associated arginine methyltranferase
cat
cathl;cathelicidin
cbl
cblb
cbp;CREB-binding protein
cbx
cc;coiled coil
cca;circadian clock associated/citrate or cis-aconitate
ccl;ccr3 ligands eotaxin
ccr;cell chemokine receptor?
cdc2;cdk protein complex?
CDK;cyclin-dependent kinase
CDKN;
cdk*rap
cd247
cd3e
ct
ceacam
cebpa ;ccaat/enhancer binding protein alpha
cebpg
cenpj
cep
cesa
cet*p
cftr;cystic fibrosis transmembrane regulator
ctr
chc;clathrin?
che;cca1 hiking expedition
chek
chrebp;carbohydrate responsive element-building protein
chk
chop
chr;channelrhodopsin
chx
cidea
cis;common insrion sites
cit
ck;casein kinase
clb
CLE4A
clib
clk
cln;syclin?
cmy;chromomethylase
cnih
cnp
cnt
CNV;copy number variation
col9a1
COMT;catechol-o-methyltransferase
cop
CORO1B
cox
cpt
creb;cyclic
crebp;camp responce element-binding protein
crhr;corticotropin-releasing hormone receptor
CRISPR;clutered regularly interspaced short palindromic repeats
crk
crkl
cry;cryptochrome
csf;colony stimulating factor
csk
cslb
cslf
cslg
cslh
csn
csnk 2A1
csp;cystein string protein
ctcf
CTLA; Cytoxic T-lymphocyte antigen
cue
cx;connexin
cxcl
cyc
cyp;cytochrome p450
cys
c3po;component 3 promoter of risc
daacs;dicarboxylate/amino-acid:cation symporter
dab
dach
daf
dag;diacylglycerol
DAO
dap
dapi;diamidino-2-phenylindole
DARC;Duffy antigen for receptor chemokine
dat
dbd;DDN
daz
dazl
A binding domain
dbc
DBP;duffy binding-protein
scakd
dcl;Dicer-like
dcn
dctn;dynactin
ddcad
ddef
ddx
dit
ddm;desreased dna methylaion
dec
dep
dgk;diacylglycerol kinase
dgkb
dhh
dhr;dock honology region
dhx
dicer
dio
disc;disrupted in schizophrenia
dll;distal-less
dlx
dmdg
dmrt;doublesex and mab-3-related transcripion factor
DNA;
dnah
dock
dppa
dr;death receptor/dopamine receptor
dram
DRD
drm;domains rearranged methyltranserase
drp;dtnamin-related protein
sb;double-strand break
dscam
dscr;down syndrome critical region
dstn
DTNBP
dym;dynamin
dyrk
eat
ebi2
ebna
ecat
eef
ef-p
egfr;epiermal-growth-factor receptor
egr
eif;eukaryotic translation initiation factor
eif4e2;
elf;early flowering
elk
elmo1
enpp
epcam;Epithelial cell adhesion molecular
epo;erythropoietin
epor
EPS8
ER;enoplasmic reticulum
eras
ERBB;e receptor
erg
erf;ethylene-response-factor
erk-map kinase;extracellular signal-regulated kinase-mitogen-activate protein kinase
erman;er mannosidase
ESR;
essrb
etv
eut
eutk
eutl
eutm
eutn
euts
evi
ews
ewsr1
exd;extradenticle
exph
eya;eyes absent
faah;fatty acid amide hydrolase
FABP;fatty acid binding protein
fadd;fas-associated death domain protein
FAC
FAM
fap
far
FBF1
fbxl;;F-box and leucine-rich repeat proein
fbxw;F-box an WD repear omainc
fcer
fcgr3a
fe
fgf ;fibroblast growth factor
fgfrdito receptor
FH;umarate hydrasate
fhbp;factor h binding protein
FISH; fluorescent in situ hybridization
fkh2
flc
flg
FLI
flj
flt
FMRP;fragile x mental retardation protein
fos
fosb
foxo
foxp;forkhead box p
fras;fraser syndrome
frem;fras1-related extracellular matrix protein
frp;frizzled-related protein
frzb
fto
ftsa
ftsaz
ftsh
ftsz
fus
fut4
fyn
gaba;y-aminobutyric acid
GABR
gab1
gab2
GAP;GTPase-activating protein
garz;gartenzwerg
gasp3
gbd'gtpase-binding domain
gca
gch;gtp cyclohydrolase
gcn;general control nonderepressible
gdf
gdnf
gdp;glyceraldehyde-phosphate dehydrogenase
gef;guanine nucleotide exchange factor
get
gga;Golgi-associated,gamma aapin ear-containing-arf
gigantea
git1
gja
gjb
gjc
gli
gln
glr
glrx
glu
glur;glutamate receptor
glut;glucose transporter
gly
glyr;glycine receptor
gm
gmp;guanosine monophosphate
gnas
gna13
gnbp;gram-negative-bacteria-biningprotein
gnpda
got;glutamate oxaloacetate transaminase
gp;g-protein?
GPCR;G-protein-coupled receptor
gpr; G-ptotein-coupled receptors
gpsn
gr;glucocorticoid receptor
grap
grasp
grb2
gria
GRIN
grinl1b
grk2;G protein-coupled receptor kinase 2
grm
grs
gsc;Glut4 sorage compartmnt
gsk;Glyvocogen synthase kinase
gsk3b
gsn
gstt;glutathione S-transferase theta
gtf2i
gtp;guanine nucleotide-binding protein
hac
hac1p
har;human accelerated region
hat;histone acetyl transferase
hb
hba
hbb
HCT;
HDAC;histone deacetylase
hds;homology-directed repair
hek;human embryonic kidney
hes
hh
hif;hypoxia-inducible factor
hipi
his
hist
hjurp
hk;hexokinase
hla;human leukocyte antigen
hla-dp
hnf
hnrnp-a
hox;homeobox
hoxd
HP
hprt;hypoxanthineguanine phosphoribosyltransferase
hr;;histamine receptor
hras
hrd
hsf
hsp;heat shock protein?
hstn;histatherin
hth;homothorax
htr;5-hydroxytryptamine receptor
HTT;human huntingtin gene
HUVECs;human umbilical vein endothelial cells
hyb
hyl
h2ax
h*k
ian*l
IDE;Insulin-degrading enzymes
idh1;isocitrate dehydrogenases
idi;isopentenyl-diphosphatate elta isomerase
ifdr
ife
ifih;intereron induced with helicase c domain
ofit
IFN;Interferon regulatory factor
ifng
ig;immunoglobulin
igfbp
ihh;indian hedgehog
ikka
ikki
ikkn
ile
ilk;integrin-linked kinase
IL1B;interleukin
inpp4a
INPP5D
ins
insp;inositol-*trisphosphate
INSR
ipk
irak;Interleukin-1 receptor-associate kinase
irap;insulin-regulate amino peptidase
ire
ires;internal ribosome entry site
irgm
irs1;insulin receptor substrate
islet
islr
ispa
itgb
jak
jhdm
jmjd
jnk ; kinase?
jun
kap
kcnh
kcnj11;potassium inwardly rectiying channel j11 gene
kcnq
kctd
kdm
kdm*a
kdr
kid
kif1a
kit
KITLG
kix
klf
klrg
kn
kndg1
krab;krippel-assocaited box
kras
krs
krt;keratin?
ksr
ksrp;KH-type splicing regulatory protein
kv
lac
lacz
lag
lamp;lysome-associated membrane protein
lbd;ligand binding domain
lbp
lcad
lck
lcp
lct;lactose
ld;linkage disequilibrium
ldh;lactate dehyrogenase
ldlr;low-density lipopretein receptor
leap
lefty
leu
lgc;ligand-gated chloride channels?
lgr
lhx
lhy;late elongated hypocotyl
lif;leukemia inhibiting factor
lilra;leukocyte immunoglobulin-like receptor
limk
LINE2long-interspersed-nuclear element
lingo
lis1
lkb
lmaf
lman
lmna
lncap
loxp
lpa;lysophosphatidic acid
lrim
lrp1
lrr;leucin-rich repeat
lsd
LTR;Long terminnal repeats
ly6e
lyg
lyn
lys
mad;mitotic arrest-deficint
maf
mafb
mafg
magfea
mal
malp
maoa
maob
map;mitogen-active protein?
mapk;MAP kinase? /mitogen-actived protein?
mapt
map2k7
mash
math
matk
MB;megabase
MC1R;melanocrotin-1 receptor
mcad
mcf
mck; muscle creatine kinase
mcl
mco;multicopper oxidase protein
mcp;monocyte chemotactic protein
mcph
mct
md;myeloid diferentation
mda;melanoma diferentiation-associated protein
mdc;meiator of dna damage checkpoint protein
mdh;malate ehydrogenase
mdm
mdy
me;malic enzyme
mecp
mek
mest
met
mfs;major facilitator superfamily
mglu;metabotropic glutaminate
mgst
mhc;major histocompatility comples
midas;metal ion-dependent adhesion site
mipol
MIR;mammalian-wide interspersed repeat
mite;minature inverted repeated transposable element
mitf
mlc;myosin light chain
mlh
mll;mixed-lineage leukaemia
mmp
mpk;MAP kinase
mras
mre
mrn;mre11/rad50/nbs1
msh
msk2
msp;merozoitic
mst1r
msx
mthf;methyl-tetrahydrofolate
MTHFR
mtnr;melatonin receptor
mtor;mammalian target of rapamycin
mybp;myosin binding protein
myc
mycn
myd
myg;myogenin
myh9
nAChR
nad;nicotinamide adenine dinucleotide
nadp;as above+phosphate
nae;nedd8-activating enzyme
nailc
nampt;nicotinamie phosphori
nanog
nat;n-acetyltransferase
nbfp;neuroblastoma break-point family
nbs;nucleotide binding site
nbs-lrr
nck1
ncoa
nedd9
negr
nek;nerer-in-mitosis A-related kinase
neto
nf2;nuclear factor?
nfkbiz
nhej;nonhomologous end joining
nhe9
nicd;notch intracellular omain
nih*t
NIMA;never-in-mitosis A
nkx
nlgn4
nmda ;N-methyl-d-asparttate
nod
notch
npm1
nppa
nppb
nptx
npyb;neoropeptide y receptor
nras
nrf;nuclear respiractory factor
nrp;nuclear rna polymerase
nrxn1;neurexin
nss;neurotransmitter;sodium symporter
nth;N-terminal helix
ntl;no tail
ntp;nicleoside triphosphate
ntrk
NUMBL
nur
oar;octopamine
oasis
OCA
oct
ol3a3
oli
olig
orc;origin recognition complex protein
osd;omission o secon ivision
ost
ot
pad;proteins associated with differention/peptidylarginine deiminase
pag
pak;p21-activated kinase
pak1
palb
park
pax
pbef
pcdh;protocadherin
pcf
pcg;polycomb group
pclkc
PCR;polymerase chain reaction
pd;programmed death
pdeb;phosphodiesterase
pdgf;platelet-derived growth factor
pdgfra
pdgfrb
pdpk1
pdr
pdx
pdz
pecam1
pep;perpetual flowering
per;period
pfk;phosphofructokinase
pg;piggybac
pgk;phosphoglycerate kinase
pgr
pgs
ph;pleckstrin homology
pha
phactr
phd;proylylhydroxylases
phe
phox2b
phyl;phyllop
pi
PI3K;phosphoinositide 3-kinase
pias2
pik3ca
pik3r1;phosphatidylinositol-3-oh kinase regulatory subunit
PIRNA
pitpnm
pkcv
pkr;protein kinase r
pla
plcg2
plk;pelle-like kinase?
plp
PLXNA
pms2
pnr;pannier
poli;polymerase iota
pot
pp;protein phosphatases
ppara;peroxine-prolierator-activated recepor a
pparg;peroxine-prolierator-activated receptor-y-gene
ppck;phosphoeenolpyruvate carboxylase kinase
ppdk;pyruvate orthophosphate dikinase
ppp*r;protein phospharase* regulator(inhibito) subunity
ppr
ppre;ppar responsive element
pr;progesterone receptor
prc;polycomb repressive complex
prdm
pre
PREF;preadipocyte factor
prickle
prkca
prkcd
prox
prp;plasticity-related proteins
prr;pseudo-responce regulator
psd
psors
ptb
ptch
ptd;phosphotyrosine-binding
pten;phosphatase and tensin holologue
ptex;plasmodium translocon od exported proteins
pthr
pth*r
ptk2B
ptpn;protein tyrosine pgosphatase-n
ptprd
ptprk
ptprt
puma
pxn;paxillin
pyl
pyr;pyrabactin resistance
p4hb;prolyl 4-hydroxylase
qsh
rab
rac
rad
raf
rage
rai1
rapgef
rara;retinoic acid reeceptor alpha
ras
rasa1
ras-grf
rassf1
rb
rbd;rac-binding omain
rbl;reticuloctyce-binding-like
rbpms
rc
rc*h
rdr;RNA-depenent RNA polymerase
rem1
ret
rex
rfv
rgs
rheb
risc;sirna-induced silencing complex
RKO
rnaset
rnd;resistance nodulation cell division
rnf5
rny
ror
rosa
RP
rpa
rps
rrt
rscS
rsks
rspo;R-spondin
rsy
rtk;receptor tyrosine kinase
rtt
rtta;reverse tetracycline transactivator
runx*t
rwpe
rxr
ryr;ryanodine receptor
saa
sae
sb;sleeping beauty
SCAP;SREBP cleavage acivating potein
SCARB2;scavenger receptor B2
scf;skp1/cullin/f-box protein
schb
scr;sex combs reduced
sdh;succinate dehydrogenase
sdt
secy
sema;semaphorin
ser;serine?
serpinb
sgms;sphingomyelin synthase
sgk;srum/glucocorticoid-regulated kinase
sh;src homology
shank3
shc1
shd
shh
shpk;sphingosine kinase
sh*b
sh*pxd*
sh-st*y
sic
sif;stumpy induction factor
sik;salt-inducible kinase
sine;short interspersed nuclear element
sir;silencing information reglator
siRNA;short interfering RNA
sirt
six
sk;snorkel
skn
sk2b1
SLAM;signalling lymphocyte activation molecule
SLC
slc1a3
slc2a1
slc9a3r2
slit
smad
smaf
smi
smn;survival motor neuron
smo;smoohtened
smt
smg
snca
sndstaphylococcal nuclease and tudor domain
snorkel
SnoRNA;small repeat nucleolar RNA
snrk;snf-related kinase
snrpn
sod;superoxide dismutase
sol
sorl1
SOS;son of sevenless
sox
sp1
spaw
spg;spartin?
sphk;sphingosine kinase?
spn;snurportin
spock
spr
spry;sprouty
src
SREBP;sterol regulatory element binding-protein
srf;serum responce factor
ssm
ssp;suspensor allele
ssr;simple sequence repeat
stat3;signal transducers and activators of transcription
stella
stk;src tyrosine kinase?
strn
suc
sur
sxc;super sex combs
syk
syn;synapsin
synj2bp
syx;syntaxin
s1p;sphingosine-1-phosphate
tacr
tacstd
Taftipsi
tagln
tarbp
tarp;transmembrane AMPA-receptor regulatory protein
tau
tb
tbs;TCP-binding site
tbx1
tcf7l2;trancription factor 7 like 2 gene
tchh
tchhl
tcp
tcr;T-cell antigen-binding receptor
tdp;threonine dehydrogenase
tdp
tec
terra;telomere-repeat-encoded rna
tert
tes
tet
tgn;trans-golgi network
tgr;transforming growth factor
tgfbr1
thap
thp
thr
thyx
ticam
tip
TLR;toll-like receptors
tmem
tmprss;transmembrane serine protease
tmprss2-erg
tnf
toc;timing of cad expression
tor;target of rapamycin
TP;tumour protein
TPCN ;tw0-pore segment channel 2
TPH;tryptophan hydroxylase
tpr;tetratricopeptide repeat
fraf
trax;translin-associated factor x
trem
trif
trim
trp
trx;trithorax
try;trypsinogen
tsc
tsh;teashirt
tsix
ttp;tristetraprolin
tuba3
tubg1
txnd;thioredoxin domain
tymp;thymidine phosphorylase
TYR; tyrosinase
TYRP; tyrosinase-related protein
uba
ubc
ubch
ube21
ube3a
ubx;ultrabithorax
UCP;uncoupling protein
ulbp
ump;uridine monophosphate
unc
upr;unfolded protein responce
usp
utr;untranslaed region
uvrag
utx
vac
val
vamp;vesicle-associate membrane protein
vasa
vav
vcap
vdr;vitamin D receptor
VEGF;vascular endothelial growth factor
vesl
vhl
vif
vimi;variant in methylation
vlcad
vldl
vlr;variable lymphocyte receptors
vmat;vesicular monoamine transporter
vrs
vsg;variant surface glycoprotein
vsig
vtc;vacuolar transporter complex
vtc*p
waxy
vps
vsx
WGS;whole-genome shotgun
wtx
wwp
xbp
xist
y
yar
ycca
yda
yhb
yjm
yoda
ypf;yellow fluorescent protein
yqid
y81g3a
zap-70;Zeta-chain-associated protein kinase 70
zc*h**a
zdhhc
zf
zfhx
zfn;zinc finger nuclease
zfp
zic
zif
zmppck
znf
zranb

Platypus Genome analysis

The platypus has 52 chromosomes in both sexes.

Genome has both reptilian and mammalian features.

Platypuses possibly go back 166 million years.

Milk protein genes;mammal-like