Wednesday 27 February 2008
P2Y2
Children who have a variant of this gene are more likely to have abnormal hair follicle cells form.
Saturday 23 February 2008
Prostate Cancer genes
Scientists are working to develop a test for prostate cancer after discovering 7 genetic markers linked to prostate cancer, each of which raised the risk by 60%.
Two of those genes are called MSMB and LMTK2.
10,000 British men die from the disease every year.
HNF1B and PTEN possibly connected to prostate cancer.
Genes that are linked to slow aceylation like versions of NAT-2 have been linked to prostate cancer.
In 50% of cases,a fusion of the TMPRSS2 and erg genes is found.
Two of those genes are called MSMB and LMTK2.
10,000 British men die from the disease every year.
HNF1B and PTEN possibly connected to prostate cancer.
Genes that are linked to slow aceylation like versions of NAT-2 have been linked to prostate cancer.
In 50% of cases,a fusion of the TMPRSS2 and erg genes is found.
RRM2P4
This gene located on the X chromosome, is believed to have originated 2 million years ago.
Some researchers believe it may have come from a Asian Homo Erectus population,whereas others believe the gene originated from Africa.
53% of people in South China have this gene.
Some researchers believe it may have come from a Asian Homo Erectus population,whereas others believe the gene originated from Africa.
53% of people in South China have this gene.
First African male genome sequenced
Illumina, a biotechnology company in San Diego, California has made the first African genome, from a Yoruban man in Nigeria.
Saturday 2 February 2008
Genes linked to heart disease
Rs10757274 and Rs1333040 on chromosome 9 boosts the risk of heart of heart disease by 40% if there is one copy of the gene, two copies double your risk of having a heart attack early in life.
The genes MUC6 AND LPA are associated with heart disease as well as H. pylori infections.
The FH(familial hypercholestrolaemia) gene gives a 50% chance of heart disease after the age of 10.
Strong miR-21 signal is associated with cardiac disease.
cdkn2a and cdkn2b
The genes MUC6 AND LPA are associated with heart disease as well as H. pylori infections.
The FH(familial hypercholestrolaemia) gene gives a 50% chance of heart disease after the age of 10.
Strong miR-21 signal is associated with cardiac disease.
cdkn2a and cdkn2b
Genes linked to diabetes
Rs10811661 on chromosome 9;people with this gene released less insulin when given glucose.
E23K variant of the KCNJ11, Lpl,TCF7L2 P12A variant of the PPARG gene and ppm1l have also been associated with diabetes.
HHEX gene variants rs1111875 and rs7923837
HLA-DQ8 and IAg7 have been closely associated with type 1 diabetes.
Mutations(rs1387153) in a gene called MTNR1B, a melatonin receptor has been linked to Type 2 diabetes, the mutation increases the risk by 9%
E23K variant of the KCNJ11, Lpl,TCF7L2 P12A variant of the PPARG gene and ppm1l have also been associated with diabetes.
HHEX gene variants rs1111875 and rs7923837
HLA-DQ8 and IAg7 have been closely associated with type 1 diabetes.
Mutations(rs1387153) in a gene called MTNR1B, a melatonin receptor has been linked to Type 2 diabetes, the mutation increases the risk by 9%
Cat genetics
Studies of 979 feral and domesticated cats from Europe, Africa and Asia suggests that there are 5 feline lineages which originated in the Fertile Crescent.
Cats have been found in graves in Cyprus circa 6500BC.
Cats coexisted with humans, feeding on rodents that infested the first farmer's grain houses.
The TYR gene in cats has been linked to coat colour.
Cats have been found in graves in Cyprus circa 6500BC.
Cats coexisted with humans, feeding on rodents that infested the first farmer's grain houses.
The TYR gene in cats has been linked to coat colour.
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