Monday 14 January 2008

Genes involved with breast cancer.

MicroRNA sequences mir-122a, mir-199, mir-206 and mir-489.

The expression of these genes are lost in the majority of breast cancer patients that relapse.

Mir-10b over expression is associated with breast cancer tumours.

A master gene called SATB1 makes breast cancer more aggressive,disabling this gene may stop breast cancer cells growing.

Involved in one type of breast cancer, TGFSS switches on a molecule called ANGPTL4.

HER2(human epidermal factor receptor 2) also known as ERBB2 is associated with breast cancer.

Higher than normal levels of IGF-1(Insulinlike growth factor) in the blood has associated with higher risk of breast cancer.

Breast cancer patients survived longer, with the protein Brd4, so research suggest.

ESR1 gene appears to be amplificed in some tests,but not others.

NQO1*2, rs1800566(t) is associated with low survival rate.

AGTR1,AKT1,PIK3CA,PTEN and TP53 genes are also associated with breast cancer.

BRCA1 and BRCA2  genes are also associated with breast cancer

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