Genes implicated in leukaemia.

Two genes called MEL and AML if fused together inside blood stem cells in bone marrow can cause leukaemia.

When scientists injected such abnormal blood cells into mice, they developed leukaemia-like symptoms.

Molecule called sumo, if attacked by an enzyme called RNF4 is destroyed.

In cases of Acute Lymphobatic Leukaemia, a gene called IKZF1 is deleted in almost 90% of cases,and a gene called CDKNZA is deleted in about 50% of cases.