Saturday 2 August 2008

Genes linked to autism

NHE9 mutations have been linked to autism.

NLGN4 gene mutations G995,K378R,R704C and V403M as well as deletions of exons 4,5 and 6 are believed to be linked to autism.

A deletion close to a gene called PCDH10 appears to be liked with autism.

Shank3 deletions has also been linked to autism.

A variant of the MET gene is more common in autistic children, who also have bowel disorders.

SNPs believe to be associate with autism include;
rs10512025
rs12293188
rs13206855
rs16910190
rs16910194
rs17088254
rs2632453
rs3763947
rs4307059
rs4742408
rs4742409
rs6477233
rs7766973
rs7923367
rs952834

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