Thursday 17 July 2008

How genes affect HIV infection

A mutation in the gene CCL5 accelerates the progression of HIV-1 in those of American European descent.

CCR5 delation is connected withproection against HIV

DARC- found in about 60% of african Americans, appears to slow the the progression of HIV.

Duffy-negativity,common among africans is also believed to increase suspectibility to HIV.

Mitchondrial DNA appears to affect progression towards AIDS.

Thoses with the U5A1 and J haplogroups progressed faster towards AIDS.

Thoses with the H3 haplogroup

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