Saturday 2 February 2008

Genes linked to diabetes

Rs10811661 on chromosome 9;people with this gene released less insulin when given glucose.

E23K variant of the KCNJ11, Lpl,TCF7L2 P12A variant of the PPARG gene and ppm1l have also been associated with diabetes.

HHEX gene variants rs1111875 and rs7923837

HLA-DQ8 and IAg7 have been closely associated with type 1 diabetes.

Mutations(rs1387153) in a gene called MTNR1B, a melatonin receptor has been linked to Type 2 diabetes, the mutation increases the risk by 9%

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